منابع مشابه
Ammonia Blood Levels and Valproic Acid
The prevalence and magnitude of valproic acid (VPA)-related hyperammonemia (HA) were estimated by a review of the literature, and the clinical symptomatology and risk factors for the development of HA determined by researchers at university hospitals in Santiago, Chile; and Rush University Medical Center, Chicago, IL. Out of 183 studies between 1980 and 2005, 24 met inclusion criteria; 7 were p...
متن کاملPlasma ammonia levels in patients treated with valproic acid
10.4172/Neuropsychiatry.1000178 © 2017 pISSN 1758-2008 eISSN 1758-2016 Neuropsychiatry (London) (2017) 7(1), 42–47 42 1Department of Psychiatry, University of Occupational and Environmental Health, Fukuoka, Japan †Author for correspondence: Prof. Reiji Yoshimura, Department of Psychiatry, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka 807...
متن کاملAssociation between the blood concentrations of ammonia and carnitine/amino acid of schizophrenic patients treated with valproic acid
BACKGROUND Administration of valproic acid (VPA) is complicated with approximately 0.9% of patients developing hyperammonemia, but the pathogenesis of this adverse effect remains to be clarified. The aim of the present study was to search for mechanisms associated with VPA-induced hyperammonemia in the light of changes in serum amino acids concentrations associated with the urea cycle of schizo...
متن کاملValproic acid and plasma levels of primidone and derived phenobarbital.
Five patients were studied to determine whether kinetic interaction occurs between valproic acid and primidone. During concurrent administration of primidone and valproic acid no significant interaction was observed. Primidone and derived phenobarbital levels did not change significantly. No adjustment of primidone dose was required when valproic acid was used as adjunctive therapy.
متن کاملVALPROIC ACID- valproic acid solution Par Pharmaceutical ----------
WARNINGS: LIFE THREATENING ADVERSE REACTIONS See full prescribing information for complete boxed warning. Hepato toxicity, including fatalities, usually during first 6 months o f treatment. Children under the age of two years and patients with mitochondrial disorders are at higher risk. Monitor patients c losely, and perform serum liver testing prior to therapy and at frequent intervals thereaf...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 2007
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-21-12-8